This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...
Oncology has risen to the forefront of genomic profiling, which is being used to identify actionable driver mutations and other markers. These markers can help clinicians design therapies and monitor ...
First in class TLR7/8 agonist BDB001 combined with atezolizumab and stereotactic body radiation therapy in patients with advanced pancreatic adenocarcinoma: Results from the AGADIR study. Impact of ...
Clinically relevant applications, such as somatic variant detection, continue to push the bounds of existing next generation sequencing (NGS) technologies, requiring highly scalable solutions that are ...
Criteria for NGS testing in MNs can reduce unnecessary tests, saving costs without affecting patient care quality. Six approval and six cancellation criteria guide appropriate NGS use, focusing on ...
Many patients with actionable driver oncogenes (ADOs) are never identified and thus never receive targeted treatment. This study evaluated the economic impact and the potential life-years gained (LYG) ...
Use of Adapter Blocking Oligos for In-Solution Hybridization Improves Target Capture Performance In-solution hybridization (target capture) has been used since the early days of next-generation ...
Indexes vary greatly and perform differently in different conditions. Some designs are predisposed to dimerization, while others are optimized at certain concentrations, and some will not be optimized ...
Andre Hudson receives funding from the National Institutes of Health. Crista Wadsworth does not work for, consult, own shares in or receive funding from any company or organization that would benefit ...
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