The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

Muscle stem cells repurpose the tenogenic factor Scx to establish a muscle-specific transcriptional program that sustains stem cell expansion, migration, differentiation, fusion, self-renewal, and ...

Researchers at the Wellcome Sanger Institute and at Sun Yat-sen University have generated what they claim is the first comprehensive atlas of aging muscles in humans. The team applied single-cell ...

Space exploration activity has been increasing. In turn, researchers are more interested than ever in uncovering more about how space travel affects human health and the progression of disease.

Skeletal muscle and cardiovascular diseases continue to pose significant challenges to public health, affecting a wide range ...

Muscles make up nearly 40% of the human body and power every move we make, from a child's first steps to recovery after ...

In a finding that opens the door to the development of targeted therapies for various muscle disorders, newly published research identifies key mechanisms of skeletal muscle regeneration and growth of ...

In work published in Nature Biotechnology, Rubin and his research group turned to 3D cell culture to take on the problem of generating sufficient satellite cells for regenerative therapies. 2 ...

How muscle changes with ageing, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of ageing muscles in humans. Researchers ...

Muscles are formed by the merging of many small myoblasts into larger myofibers. This fusion of mononucleated myoblasts with a single nucleus into multinucleated myofibers with multiple nuclei is an ...