UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving ...

Using a variety of laboratory and animal models, the team found that cysteine fuels the production of the antioxidant ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized ...

In solid tumours, such as breast and colon cancers, dendritic cells are not only rare but also defective. Without functional ...

Illustration of a T lymphocyte white blood cell, depicted in blue, attacking a cancer cell, shown in red Nemes Laszlo / Science Photo Library via Getty Images CAR T-cell therapy can be a lifesaving ...

Researchers at Umeå University have contributed new insights into how cancer cells protect themselves from cell death. The ...

Reducing calorie intake helps cancer-fighting immune cells do their jobs more effectively, reports a study by Van Andel Institute scientists and collaborators. The findings lay the groundwork for ...

Scientists have uncovered new genetic rules that determine whether the immune system’s “killer” T cells remain powerful long-term defenders or become worn out and ineffective. By building a detailed ...

The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...