Proteolytic degradation products of fibrinogen, produced as a result of excessive fibrinolysis, have been demonstrated in the blood of cirrhotic patients. 7,8 Such degradation products, when formed in ...

The first study to examine the effects of whole-chocolate consumption on ex vivo platelet function has shown that dark chocolate acutely reduces collagen-stimulated platelet aggregation and reduces ...

Approximately 40% of adolescent women experience heavy menstrual bleeding (HMB), and 10–62% of them have an underlying bleeding disorder (BD). Diagnosing a BD remains challenging because of ...

Abnormalities of platelet function in some patients with primary, but sporadic, disorders of hemostasis have been attributed to impaired release of platelet adenosine diphosphate (ADP). This defect ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

A major factor in coronavirus disease 2019 (COVID-19)-associated mortality is the development of coagulation abnormalities that may result in thromboembolism. Human platelets have been found by ...

A platelet aggregation test checks how well your platelets clump together to form blood clots. Platelets are a type of blood cell. They help form blood clots by sticking together. A clot is what stops ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) bears an abundance of the characteristic spike protein, which mediates its entry into and fusion with the host cell, as well as ...

Platelet function may aid in determining disease severity for patients with psoriasis who are at an increased risk of developing cardiovascular disease (CVD) and increased inflammation, a review notes ...

Moderate alcohol consumption is believed to reduce mortality from cardiovascular disease. Binge drinking, on the other hand, is known to increase mortality from all causes. Recent findings indicate ...

It is clear from the available literature that much of the evidence supporting treatment recommendations for uremic bleeding comes from studies performed 25–30 years ago. At that time, medical care ...