The act of rising from a chair may seem like a simple task for most, but it is actually a significant effort for many older adults. This small movement serves as an everyday way to gauge overall ...

Explore how clinical multi-omics integration drives systems medicine, detailing data fusion methodologies and lab ...

Thin stretches of the human X chromosome look oddly empty when you scan for Neanderthal DNA. Geneticists even have a name for the gaps: “Neanderthal deserts.

Non-inferiority trials are a valuable type of clinical trial to evaluate new treatments that might have differing benefits. Such trials are increasingly used, but have methodological challenges in ...

The evidence is solid but not definitive, as the conclusions rely on the absence of changes in spatial breadth and would benefit from clearer statistical justification and a more cautious ...

The lead drug candidate, ALN1003, showed dose-related body weight loss and favorable body composition changes in the DIO mouse modelALN1003 also ...

Objectives Parkinson’s disease (PD) is a complex, progressive neurological disorder with motor and non-motor symptoms. Among the non-motor symptoms, constipation severely affects the patients’ quality ...

Objective A panel of antibodies against three antigens, University Hasselt (UH)-rheumatoid arthritis (RA).305, 318 and 329, has been associated with lack of response to first-line therapy in the Care ...

Medicaid managed care organizations should prioritize children in low-opportunity neighborhoods to optimize health care utilization, improve minority health, and address health-related social needs.

Objectives To estimate the rate of hospitalisation, identify associated factors and assess out-of-pocket expenditure (OOPE) among adults with multimorbidity in Kerala, India. Design Community-based ...

1 Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA 2 Department of Epidemiology, Harvard T H ...