Duchenne muscular dystrophy (DMD) is a severe X-linked myopathy characterised by progressive skeletal and cardiac muscle degeneration, loss of ambulation, respiratory failure and premature mortality.

Anavex’s precision medicine approach recognizes that Alzheimer’s pathology is heterogeneous, but autophagy dysfunction represents a causative co-factor that precedes divergent downstream ...

Ovarian cancer (OC) is a "silent killer" with an annual incidence of 11.2 per 100,000 and mortality of 7.6 per 100,000. Most cases are diagnosed at ...

A new study shows p62-mediated Mallory-Denk body formation is an adaptive, protective response to alcohol-induced liver ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

Anavex Life Sciences Corp. AVXL on Friday announced that a new peer-reviewed study published by the University of California in Proceedings of the National Academy of Sciences, Nexus supports the ...

Cells face constant threats from inside and out. Thus, they’ve evolved sophisticated stress response pathways such as the unfolded protein response (UPR), ...

Long-term exposure to the pesticide chlorpyrifos was associated with more than a 2.5-fold higher risk of Parkinson’s disease. The study combined hu ...

Funding supports IND-enabling activities for Casma’s CSM-101, a first-in-class TRPML1 agonist targeting lysosomal dysfunction in genetically driven neurodegenerative diseasesCAMBRIDGE, ...

A research team led by Professor Ki-Young Lee at the College of Medicine, Sungkyunkwan University, has uncovered a previously unrecognized tumor-intrinsic role of the immune checkpoint molecule PD-L1, ...